ethyl trans-2-(2,4,5-trifluorophenyl)cyclopropane-1-carboxylate - Names and Identifiers
ethyl trans-2-(2,4,5-trifluorophenyl)cyclopropane-1-carboxylate - Introduction
ethyl trans-2-(2,4,5-trifluorophenyl)cyclopropane-1-carboxylate is an organic compound with the chemical formula C13H11F3O2.
Nature:
-Appearance: White crystal or crystalline powder
-Melting point: 68-72 ° C
-Boiling Point: 347-348 ° C
-Density: 1.361g/cm³
Use:
ethyl trans-2-(2,4,5-trifluorophenyl)cyclopropane-1-carboxylate is an important organic synthesis intermediate with a wide range of applications:
-In drug synthesis, it can be used to synthesize a variety of bioactive molecules, such as anti-cancer drugs, anti-diabetic drugs, etc.
-In pesticide synthesis, it can be used to synthesize pesticides.
-In the cosmetics industry, it can be used to synthesize certain fragrance ingredients.
Method:
The preparation of ethyl trans-2-(2,4,5-trifluorophenyl)cyclopropane-1-carboxylate is usually carried out by the following steps:
1. First, ethyl 2,4, 5-trifluorobenzoate was reacted with bromoethane to obtain ethyl 2-(2,4, 5-trifluorophenyl) acetate.
2. Then, the above product and cyclopropane are subjected to a reduction reaction of lithium aluminum nitride to obtain ethyl trans-2-(2,4,5-trifluorophenyl)cyclopropane-1-carboxylate.
Safety Information:
ethyl trans-2-(2,4,5-trifluorophenyl)cyclopropane-1-carboxylate is a chemical that requires the following safety information:
-May be irritating to skin, eyes and respiratory tract, avoid direct contact when using.
-in the process of operation, need to take good ventilation measures, avoid inhalation of its steam or dust.
-Wear appropriate personal protective equipment such as gloves, goggles, etc.
-When storing, should be placed in a cool, dry place, and away from fire and oxidant.
-If accidentally splashed on eyes or skin, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 21:01:54